Tag: Timothy Földes
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Looking forward to the next year! Lab Retreat 2025
We spent a beautiful lab retreat day at the MIT Endicott House, touring the grounds, reflecting on the past year, and setting strategy for the year ahead. In the afternoon we got creative capturing shadows with cyanotypes, imprinting porcelain cups, and creating custom flatbreads and ice cream sundaes with our friends and families. Thank you…
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Henrik Dahl Pinholt to present at Cold Spring Harbor Laboratory
A BASELINE MODEL OF POLYMER-DRIVEN TRANSCRIPTION FOR ENHANCER-DRIVEN GENE ACTIVATION Henrik D Pinholt1,2, TimothyFoldes2, LeonidMirny1,2 1Massachusetts Institute of Technology, Department of Physics, Cambridge, MA 2Massachusetts Institute of Technology, Institute for Medical Engineering and Science, Cambridge, MA Enhancers are key regulators of cellular decisions. They manage to convert transcription factor binding into target promoter activation with…
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Smc5/6 association with microtubules controls dynamic pericentromeric chromatin folding
Ànnia Carré-Simon, Renaud Batrin, Sarah Isler, Henrik Dahl Pinholt, Timothy Földes, Guillaume Laflamme, Maria Barbi, Leonid Mirny, Damien D’Amours, Emmanuelle FabreSmc5/6 association with microtubules controls dynamic pericentromeric chromatin foldingbioRxiv 2024.11.13.623393; doi: https://doi.org/10.1101/2024.11.13.623393 Abstract Centromeres and pericentromeres are specialized chromatin regions whose organization is critical for proper chromosome segregation through dynamic microtubule attachment. Smc5/6, highly enriched…
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Welcome Tingran Wang!
Tingran Wang, doctoral student in the MIT physics Department will be joining our lab for a 3-month rotation. During his rotation, Tingran will be collaborating with Henrik Pinholt and Timothy Foldes. They will be investigating how stretched chromatins in vivo can tell us more about their polymer properties, and eventually directly see evidence of loop…
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Science, Sun, and Seaworms. Falmouth 2024
The lab escaped to Falmouth for 4 days of science and summer. We had two days packed with talks by lab members and guests (Johan Gibcus and Anders Hansen) where we caught up on each other’s work and discussed the exciting directions our research is heading in the next year. We were lucky to visited…