Home Research People Publications Courses & Seminars

Fall 2012

HST.508/Biophysics 170: Quantitative Genomics
Leonid Mirny, Shamil Sunyaev
First meeting of the class Septemebr 12
see course calendar

Nov-Dec 2010

Evolution and biophysics of the genome
Leonid Mirny
A short course (8 lectures) at EPFL (ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE)
as a part of Physique de la matiere vivante

Fall 2010

Quantitaive Genomics
Leonid Mirny, Shamil Sunyaev, Gregory Krykov, Isaac Kohane

Fall 2009

8.593J - HST.452J: Statistical Physics in Biology
Mehran Kardar, Leonid Mirny

Fall 2008

HST.508: Quantitative Genomics

Provides a foundation in the following four areas: evolutionary and population genetics; comparative genomics; structural genomics and proteomics; and functional genomics and regulation. Each module consists of four lectures providing key background material, one lecture providing clinical correlates and one guest lecture from leaders in the field.

Fall 2007

HST.508: Quantitative Genomics
L. Mirny, I. Kohane, S. Sunyaev

Provides a foundation in the following four areas: Evolutionary and Population Genetics; Comparative Genomics; Structural Genomics and Proteomics; and Functional Genomics and Regulation. Each module consists of four lectures providing key background material, one lecture providing clinical correlates and one guest lecture from leaders in the field.

Spring 2007

8.593J - HST.452J: Statistical Physics in Biology
Mehran Kardar, Leonid Mirny
Open Courseware webpage of the class (2005)

A survey of problems at the interface of statistical physics and modern biology: Bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, phylogenetic trees. Physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, elements of protein folding. Considerations of force, motion, and packaging; protein motors, membranes. Collective behavior of biological elements; cellular networks, neural networks, evolution.

Fall 2005

HST.508: Quantitative Genomics
L. Mirny, A. Kho, I. Kohane, S. Sunyaev

Provides a foundation in the following four areas: Evolutionary and Population Genetics; Comparative Genomics; Structural Genomics and Proteomics; and Functional Genomics and Regulation. Each module consists of four lectures providing key background material, one lecture providing clinical correlates and one guest lecture from leaders in the field. Required for all HST students in the Bioinformatics and Integrative Genomics training program within MEMP.

Spring 2005

8.593J - HST.452J: Statistical Physics in Biology (Open Courseware) (Course website)
Mehran Kardar, Leonid Mirny

1.021/2.030/3.021j/10.333/18.361/22.00/HST.558: Introduction to Modeling and Simulation (Open Courseware)
M. Bazant, G. Ceder, N. Hadjiconstantinou, N. Marzari, L. Mirny, A. Powell, R. Radovitzky, R. Rosales, B. Trout, F. -J. Ulm, J. White, S. Yip

Basic concepts of computer modeling in science and engineering using discrete particle systems and continuum fields. Techniques and software for statistical sampling, simulation, data analysis and visualization. Use of statistical, quantum chemical, molecular dynamics, Monte Carlo, mesoscale and continuum methods to study fundamental physical phenomena encountered in the fields of computational physics, chemistry, mechanics, materials science, biology, and applied mathematics. Applications drawn from a range of disciplines to build a broad-based understanding of complex structures and interactions in problems where simulation is on equal-footing with theory and experiment. Term project allows development of individual interest. Student mentoring by a coordinated team of participating faculty from across the Institute.

Group Meetings